Explore high-dimensional biology with BD Biosciences Single-Cell Multiomics Reagents, which empower you to simultaneously detect hundreds of genes and proteins at a single-cell resolution.
Choose from an array of single-cell multiomics reagents designed to work together to enable a variety of research application.
Choose from an array of single-cell multiomics reagents designed to work together to enable a variety of research application.
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| BD® OMICS-Guard Sample Preservation Buffer | BD® AbSeq Antibody-Oligos | BD® Single-Cell Multiplexing Kit | BD Rhapsody™ ATAC-Seq Assays | BD Rhapsody™ Whole Transcriptome Analysis (WTA) Amplification Kit | BD Rhapsody™ TCR/BCR Next Multiomic Assays | BD Rhapsody™ Targeted mRNA Kits | |
| Sample preservation for RNA-seq, CITE-seq, immune profiling assays | Y | – | – | – | – | – | – |
| Protein analyses (cell surface and intracellular) | – | Y | – | – | – | – | – |
| CITE-seq | – | Y | – | – | Y | – | Y |
| Epigenomics | – | – | – | Y | – | – | – |
| Epigenome + Whole transcriptome | – | – | – | Y | Y | – | – |
| Immune profiling + Whole transcriptome | – | – | – | – | Y | Y | – |
| Immune profiling + Targeted gene analyses | – | – | – | – | – | Y | Y |
| Immune profiling + CITE-seq | – | Y | – | – | Y | Y | – |
| Multiplex samples | Y | Y | Y | – | Y | Y | Y |
View the supporting BD Rhapsody™ Accessory Kits.
BD® OMICS-One Protein Panels
CITE-seq becomes more accessible with BD® OMICS-One Protein Panels. These pre-titrated lyophilized antibody-oligo panels are designed to uncover different cell lineages and assess activation and suppression states in your single cell samples with ease. The SMART panel design approach embedded in the BD® OMICS-One Protein Panels lowers sequencing cost without compromising sensitivity or data resolution. Designed and optimized to work on the BD Rhapsody™ Single-Cell Analysis System, BD® OMICS-One Protein Panels are tested to work seamlessly with whole transcriptome, targeted and immune profiling RNA-Seq assays.
BD Rhapsody™ ATAC-Seq Kits and Protocols
Uncover new regulatory connections shaping cellular identity and function with BD Rhapsody™ ATAC-Seq Assays. Our assays offer the flexibility to profile accessible chromatin independently or you can pair them with the BD Rhapsody™ WTA Assay for multiomic analyses, enabling you to simultaneously capture both the regulatory chromatin landscapes and the transcriptional outputs in the same cells.
BD Rhapsody™ TCR/BCR Next Assay Kits and Protocols
Gain an enhanced view of immune diversity with the BD Rhapsody™ TCR/BCR Next Multiomic Assays. Efficiently characterize the antigen receptor repertoires across individual T and B cells within your sample. Choose between the BD Rhapsody™ WTA or Targeted mRNA Assays for gene expression analysis and add BD® AbSeq Antibody-Oligos to perform multiomic analyses.
BD®OMICS-Guard Sample Preservation Buffer
Use this biological sample preservation solution to protect transcriptomic and proteomic information for up to 72 hours at 4 °C. This buffer can be used for various downstream applications, including single-cell RNA-seq, CITE-seq, flow cytometry and qPCR.
BD®AbSeq Assay
Perform CITE-seq analyses for simultaneous detection of gene and protein expression. Named one of the top 10 innovations by The Scientist magazine, the BD® AbSeq Assay enables interrogation of tens to hundreds of cell-surface and intracellular protein markers in a single experiment. The BD® AbSeq Antibody-Oligonucleotides integrate seamlessly with a catalog of RNA assays to serve as a single multiomics solution.
BD Rhapsody™ Targeted mRNA Kits
Efficiently screen hundreds of genes at once. Predesigned targeted panels such as the Onco-BC, immune response and T-cell panels are available to support your research needs. Supplement these panels with your genes of interest or generate totally new custom panels that fit your research. The panels are designed to target and focus only on genes of interest and can help reduce sequencing costs.
BD Rhapsody™ Whole Transcriptome Analysis (WTA) Amplification Kits
Uncover the whole transcriptome of a single cell. The WTA amplification kit enables unbiased 3'-based capture, amplification and detection of whole transcriptomes at a single-cell level. You can identify the most differentially expressed genes in your samples and use that information to construct a targeted panel for further analysis.
BD® Single-Cell Multiplexing Kit
Combine and process up to 24 different samples together onto a single BD Rhapsody™ Cartridge. This kit is compatible with all BD Rhapsody™ Single-Cell Assays and includes streamlined informatics tools to automatically demultiplex sample tags and identify individual samples during data analysis.
Our History and Leadership in Single-Cell Multiomics Reagents
The BD Biosciences Single-Cell Multiomics Reagents extend the remarkable capabilities of our applications and instruments to multiomics, enabling the analysis of hundreds of genes, proteins and clonotypes.
The high-throughput proteomics analysis combined with RNA assays that utilize next-generation sequencing enables you to uncover the full potential of high-dimensional biology.
The BD Biosciences Single-Cell Multiomics Reagents can be used in a wide array of applications, including phenotypic and deep characterization of cell types, identifying the clonotype and the multiomic profile of T and B cells, biomarker development, vaccine research, exploring the cellular etiology of infections and pathologies, translational immunology and immuno-oncology.
Quality and reproducibility of results
Our reagents have undergone rigorous testing to produce consistent and reliable results across multiple cell types and workflows.
Integration with the single-cell workflow
Designed to work seamlessly with our advanced BD Rhapsody™ Single-Cell Analysis System, our reagents and assays are designed to support you through various stages of the single-cell workflow—from labeling your targets with oligo-tagged antibodies to preparing sequencing-ready libraries.
Compatibility with our powerful bioinformatics tools, such as SeqGeq™ Software, helps you analyze single-cell results to discern the biology and gain meaningful insights.
New frontiers in high-dimensional biology
Together with our single-cell multiomics instruments, our reagents help you push the limits of your capabilities and reach new heights in high-throughput single-cell analysis.
